论文标题

皮质表面的关节重建和分层

Joint Reconstruction and Parcellation of Cortical Surfaces

论文作者

Rickmann, Anne-Marie, Bongratz, Fabian, Pölsterl, Sebastian, Sarasua, Ignacio, Wachinger, Christian

论文摘要

大脑MRI扫描中脑皮质表面的重建对分析脑形态的分析和检测神经退行性疾病(如阿尔茨海默氏病)(AD)的皮质稀疏。此外,要对萎缩模式进行细粒度分析,需要将皮质表面划分为单个大脑区域。对于以前的任务,最近提出了强大的深度学习方法,这些方法在几秒钟内从输入MRI扫描中提供了非常精确的组织边界的大脑表面。但是,这些方法并不具有提供重建表面的分析的能力。取而代之的是,已经开发了单独的脑部促进方法,这些方法通常考虑给定的皮质表面,通常是用freeSurfer进行的。在这项工作中,我们提出了两个基于图形分类分支的选项,另一个基于一个基于新颖的Generic 3D重建损失的选项,以增强模板形成算法,以便表面网格直接带有基于Atlas的脑部扇形。通过将这两种选项与两种最新的皮质表面重建算法相结合,我们将骰子得分为90.2(图分类分支)和90.4(新的重建损失),以及最先进的表面。

The reconstruction of cerebral cortex surfaces from brain MRI scans is instrumental for the analysis of brain morphology and the detection of cortical thinning in neurodegenerative diseases like Alzheimer's disease (AD). Moreover, for a fine-grained analysis of atrophy patterns, the parcellation of the cortical surfaces into individual brain regions is required. For the former task, powerful deep learning approaches, which provide highly accurate brain surfaces of tissue boundaries from input MRI scans in seconds, have recently been proposed. However, these methods do not come with the ability to provide a parcellation of the reconstructed surfaces. Instead, separate brain-parcellation methods have been developed, which typically consider the cortical surfaces as given, often computed beforehand with FreeSurfer. In this work, we propose two options, one based on a graph classification branch and another based on a novel generic 3D reconstruction loss, to augment template-deformation algorithms such that the surface meshes directly come with an atlas-based brain parcellation. By combining both options with two of the latest cortical surface reconstruction algorithms, we attain highly accurate parcellations with a Dice score of 90.2 (graph classification branch) and 90.4 (novel reconstruction loss) together with state-of-the-art surfaces.

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