永久观察研究：支持有效实施观察性研究和在传染病领域的随机试验的新策略

论文标题

永久观察研究：支持有效实施观察性研究和在传染病领域的随机试验的新策略

Perpetual Observational Studies: New strategies to support efficient implementation of observational studies and randomized trials in the infectious diseases arena

论文作者

Hassoun-Kheir, N., van Werkhoven, C. H., Dunning, J., Jaenisch, T., van Beek, J., Bielicki, J., Butler, C., Francois, B., Harbarth, S., Padilla, A. C. Hernandez, Horby, P., Koopmans, M., Lee, J., Rodriguez-Baño, J., Tacconelli, E., Themistocleous, Y., van der Velden, A. W., Bonten, M., Goossens, H., de Kraker, M. E. A.

论文摘要

新兴的传染病和抗菌素耐药性的威胁日益增加，需要更高效的高质量研究。嵌套在临床研究网络中的永久观察研究（POS）可以改善介入和观察性研究的计划，质量和效率，尽管需要评估现实生活中的好处和挑战。 Ecraid（欧洲传染病临床研究联盟）已开始POS，并将监测对五种特定传染性综合征的影响。

The increasing threat of emerging infectious diseases and antimicrobial resistance requires more efficient, high-quality research. Perpetual Observational Studies (POS) nested within a clinical research network can improve planning, quality and efficiency of interventional and observational studies, although real-life benefits and challenges need to be assessed. Ecraid (European Clinical Research Alliance on Infectious Diseases) has initiated POS and will monitor the impact for five specific infectious syndromes.

下载PDF全文

下载文献需遵守相关版权规定

论文标题