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The increasing number of space missions may overwhelm ground support infrastructure, prompting the need for autonomous deep-space guidance, navigation, and control (GN\&C) systems. These systems offer sustainable and cost-effective solutions, particularly for asteroid missions that deal with uncertain environments. This study proposes a paradigm shift from the proposals currently found in the literature for autonomous asteroid exploration, which inherit the conservative architecture from the ground-in-the-loop approach that relies heavily on reducing uncertainties before close-proximity operations. Instead, it advocates for robust guidance and control to handle uncertainties directly, without extensive navigation campaigns. From a series of conservative assumptions, we demonstrate the feasibility of this autonomous GN\&C for robotic spacecraft by using existing technology. It is shown that a bolder operational approach enables autonomous spacecraft to significantly reduce exploration time by weeks or months. This paradigm shift holds great potential for reducing costs and saving time in autonomous missions of the future.