论文标题
使用TOMVIZ的电子断层扫描期间的实时3D分析
Real-time 3D analysis during electron tomography using tomviz
论文作者
论文摘要
对高通量电子断层扫描的需求正在迅速增加生物学科学和物质科学。但是，这种3D成像技术是通过对齐和重建的计算瓶颈，它的运行时间为几个小时到几天。我们展示了具有动态3D断层扫描可视化的实时层析成像，以便在电子显微镜上收集数据时立即对样品结构进行快速解释。使用几何复杂的手性纳米颗粒，我们显示体积解释可以在不到10分钟的时间内开始，并且在30分钟内提供了高质量的断层图。实时断层扫描已集成到Tomviz，Tomviz是一种开源和跨平台3D分析工具，其中包含直观的图形用户界面（GUI），以使任何科学家能够表征3D中的生物学和材料结构。
The demand for high-throughput electron tomography is rapidly increasing in biological and material sciences. However, this 3D imaging technique is computationally bottlenecked by alignment and reconstruction which runs from hours to days. We demonstrate real-time tomography with dynamic 3D tomographic visualization to enable rapid interpretation of specimen structure immediately as data is collected on an electron microscope. Using geometrically complex chiral nanoparticles, we show volumetric interpretation can begin in less than 10 minutes and a high quality tomogram is available within 30 minutes. Real time tomography is integrated into tomviz, an open source and cross platform 3D analysis tool that contains intuitive graphical user interfaces (GUI) to enable any scientist to characterize biological and material structure in 3D.
