论文标题

热波动诱导的囊泡形成

Vesicle formation induced by thermal fluctuations

论文作者

Gallen, Andreu F., Romero-Arias, J. Roberto, Barrio, Rafael A., Hernandez-Machado, Aurora

论文摘要

裂变和囊泡形成的过程取决于将分裂的膜的几何形状。例如,由于缺乏从何处开始该过程的弯曲区域,因此很难形成囊泡。在这里,我们表明可以通过使用具有高斯曲率的膜相模型来促进囊泡形成。我们发现波动和囊泡阶段之间的相变,取决于温度,自发曲率以及弯曲和高斯模量之间的比率。我们分析了这些过程的能量动力学行为,发现主要驱动成分是高斯能量项,尽管曲率能量术语通常也有助于该过程。我们还发现,化学电位可用于研究系统的温度。最后,我们解决了温度如何改变所有几何形状的自发囊泡条件,使其在高斯模量的更广泛范围内发生。

The process of fission and vesicle formation depends on the geometry of the membrane that will split. For instance, a flat surface finds it difficult to form vesicles because of the lack of curved regions where to start the process. Here we show that vesicle formation can be promoted by temperature, by using a membrane phase field model with Gaussian curvature. We find a phase transition between fluctuating and vesiculation phases that depends on temperature, spontaneous curvature, and the ratio between bending and Gaussian moduli. We analysed the energy dynamical behaviour of these processes and found that the main driving ingredient is the Gaussian energy term, although the curvature energy term usually helps with the process as well. We also found that the chemical potential can be used to investigate the temperature of the system. Finally we address how temperature changes the condition for spontaneous vesiculation for all geometries, making it happen in a wider range of values of the Gaussian modulus.

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