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The consideration of the holographic dark energy approach and matter creation effects in a single cosmological model is carried out in this work accordingly, we discuss some cases of interest. We test this cosmological proposal against recent observations. Considering the best fit values obtained for the free cosmological parameters, the model exhibits a transition from a decelerated cosmic expansion to an accelerated one. The deceleration-acceleration transition can not be determined consistently from the coincidence parameter for this kind of model. At effective level the parameter state associated to the whole energy density contribution describes a quintessence scenario in the fluid analogy at present time.