论文标题

MRI图像中的导管内乳头粘膜肿瘤(IPMN)分类的神经变压器

Neural Transformers for Intraductal Papillary Mucosal Neoplasms (IPMN) Classification in MRI images

论文作者

Salanitri, Federica Proietto, Bellitto, Giovanni, Palazzo, Simone, Irmakci, Ismail, Wallace, Michael B., Bolan, Candice W., Engels, Megan, Hoogenboom, Sanne, Aldinucci, Marco, Bagci, Ulas, Giordano, Daniela, Spampinato, Concetto

论文摘要

胰腺中的癌前囊肿或肿瘤的早期检测是一项具有挑战性且复杂的任务,可能导致更有利的结果。一旦检测到,还必须准确地对IPMN进行评分,因为低风险IPMN可以在监视计划下进行,而高危IPMN必须在变成癌症之前先手术切除。 IPMN分类的当前标准(Fukuoka等)显示出明显的操作员内和跨操作员变异性,除了容易出错,使适当的诊断不可靠。通过深度学习范式,人工智能的既定进展可能为有效支持胰腺癌的医疗决策提供了关键工具。在这项工作中,我们提出了一种基于AI的新型IPMN分类器,该趋势利用了Transformer网络最近在包括视觉方面的各种任务(包括视觉的任务)上概括的最新成功。我们特别表明,我们的基于变压器的模型比标准卷积神经网络更好地利用了预训练,从而支持了视觉中变压器所寻求的建筑普遍存在,包括医学图像域,并可以更好地解释获得的结果。

Early detection of precancerous cysts or neoplasms, i.e., Intraductal Papillary Mucosal Neoplasms (IPMN), in pancreas is a challenging and complex task, and it may lead to a more favourable outcome. Once detected, grading IPMNs accurately is also necessary, since low-risk IPMNs can be under surveillance program, while high-risk IPMNs have to be surgically resected before they turn into cancer. Current standards (Fukuoka and others) for IPMN classification show significant intra- and inter-operator variability, beside being error-prone, making a proper diagnosis unreliable. The established progress in artificial intelligence, through the deep learning paradigm, may provide a key tool for an effective support to medical decision for pancreatic cancer. In this work, we follow this trend, by proposing a novel AI-based IPMN classifier that leverages the recent success of transformer networks in generalizing across a wide variety of tasks, including vision ones. We specifically show that our transformer-based model exploits pre-training better than standard convolutional neural networks, thus supporting the sought architectural universalism of transformers in vision, including the medical image domain and it allows for a better interpretation of the obtained results.

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