论文标题

细胞分裂的热力学和热经济学在核中存在外源物质的情况下

Thermodynamics and thermoeconomics of cell division in presence of exogenous materials in nucleus

论文作者

Kang, Bin

论文摘要

细胞分裂是一个基本的生物学过程,细胞分裂的调节与许多重要的生物学和医学领域相关。已经对外源物质(例如纳米颗粒)引入细胞核,已经对细胞核进行了研究以调节细胞的分裂。在此,我们从能量学的一般观点考虑了这种现象。通过分析细胞分裂过程中的热力学,我们研究了细胞分裂的最佳对称性以及纳米颗粒对能屏障的影响。细胞核内的纳米颗粒的存在可能会在细胞因子或其他阶段之前阻止细胞,从而调节细胞分裂。

Cell division is an essential biological process, and regulation of cell division is of relevance for many important fields of biology and medicine. Introducing exogenous substances, such as nanoparticles, into the nucleus, has been experimentally studied to regulate the division of cells. Herein we considered this phenomenon from a general view of energetics. Through analyzing the thermodynamics during the cell division process, we investigated the optimal symmetry for cell division and the effect of nanoparticles on the energy barriers. The presence of nanoparticles inside cell nucleus might arrest cells before cytokinesis or other stages, thereby regulate the cell division.

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