论文标题
在有吸引力的表面相互作用的情况下，半串联聚合物通过锥形通道的驱动易位
Driven translocation of a semiflexible polymer through a conical channel in the presence of attractive surface interactions
论文作者
论文摘要
我们研究了半灵聚合物通过具有吸引人的表面相互作用的圆锥形通道的易位，并且在通道内空间变化的驱动力。使用柔性聚合物通过扩展通道作为控制的易位动力学的结果，我们首先表明该通道的不对称形状会在总易位时间中随着通道的顶点的函数而在总易位时间中产生非单调特征。单个单体珠在通道内的等待时间分布显示出独特的特征，这很大程度上取决于驱动力和表面相互作用。聚合物刚度导致通道的所有角度的易位时间更长。此外，随着聚合物变得更硬，易位时间中的非单调特征会大大变化，这反映在等待时间分布的变化特征中。我们构建了在低力制度中结合熵和能量贡献的系统的自由能描述，以解释模拟结果。
We study the translocation of a semiflexible polymer through a conical channel with attractive surface interactions and a driving force which varies spatially inside the channel. Using the results of the translocation dynamics of a flexible polymer through an extended channel as control, we first show that the asymmetric shape of the channel gives rise to non-monotonic features in the total translocation time as a function of the apex angle of the channel. The waiting time distributions of individual monomer beads inside the channel show unique features strongly dependent on the driving force and the surface interactions. Polymer stiffness results in longer translocation times for all angles of the channel. Further, non-monotonic features in the translocation time as a function of the channel angle changes substantially as the polymer becomes stiffer, which is reflected in the changing features of the waiting time distributions. We construct a free energy description of the system incorporating entropic and energetic contributions in the low force regime to explain the simulation results.
