论文标题

熵产生速率的估计可以空间解决细胞闪烁的活动性质

Estimate of entropy generation rate can spatiotemporally resolve the active nature of cell flickering

论文作者

Manikandan, Sreekanth K, Ghosh, Tanmoy, Mandal, Tithi, Biswas, Arikta, Sinha, Bidisha, Mitra, Dhrubaditya

论文摘要

我们使用短期推理方案(Manikandan,Gupta和Krishnamurthy,Phys。Rev.Lett。124,120603,2020),在随机热力学的框架内获得,从而从脑部反射微观的脑膜反射显微镜产生的闪烁数据中推断出较低至熵的生成速率。我们可以清楚地将活性细胞膜与ATP耗尽的自我区分,甚至时空解决活动,以下至约1 $ $ m的尺度。我们对活动的估计是独立的模型。

We use the short-time inference scheme (Manikandan, Gupta and Krishnamurthy, Phys. Rev. Lett. 124, 120603, 2020), obtained within the framework of stochastic thermodynamics, to infer a lower-bound to entropy generation rate from flickering data generated by Interference Reflection Microscopy of HeLA cells. We can clearly distinguish active cell membranes from their ATP depleted selves and even spatio-temporally resolve activity down to the scale of about one $μ$m. Our estimate of activity is model--independent.

扫码加入交流群

加入微信交流群

微信交流群二维码

扫码加入学术交流群,获取更多资源