论文标题

胃组织病理学亚大小图像分类的比较研究:从线性回归到视觉变压器

A Comparative Study of Gastric Histopathology Sub-size Image Classification: from Linear Regression to Visual Transformer

论文作者

Hu, Weiming, Chen, Haoyuan, Liu, Wanli, Li, Xiaoyan, Sun, Hongzan, Huang, Xinyu, Grzegorzek, Marcin, Li, Chen

论文摘要

胃癌是世界上第五大最常见的癌症。同时,它也是第四大致命癌症。癌症的早期发现是治疗胃癌的指南。如今,计算机技术已迅速发展,以帮助医生诊断胃癌的病理图片。合奏学习是提高算法准确性的一种方式,与互补性类型一起寻找多个学习模型是合奏学习的基础。在此实验平台中探索机器性能不足时,副尺寸病理学图像分类器的互补性。我们在GashissDB数据库上选择七个经典的机器学习分类器和四个深度学习分类器进行分类实验。其中,经典的机器学习算法提取五个不同的图像虚拟功能,以匹配多个分类器算法。对于深度学习,我们选择三个卷积神经网络分类器。此外,我们还选择了一个基于变压器的新型分类器。实验平台进行了大量的经典机器学习和深度学习方法,表明GashissDB上不同分类器的性能存在差异。分类器存在经典的机器学习模型,这些模型对异常类别进行分类非常好,而在正常类别中脱颖而出的分类器也存在。深度学习模型也存在多种可以互补性的模型。当机器性能不足时,选择合适的分类器进行集合学习。这个实验平台表明,多个分类器确实是互补性,并且可以提高集成学习的效率。这可以更好地帮助医生诊断,改善胃癌的检测并提高治愈率。

Gastric cancer is the fifth most common cancer in the world. At the same time, it is also the fourth most deadly cancer. Early detection of cancer exists as a guide for the treatment of gastric cancer. Nowadays, computer technology has advanced rapidly to assist physicians in the diagnosis of pathological pictures of gastric cancer. Ensemble learning is a way to improve the accuracy of algorithms, and finding multiple learning models with complementarity types is the basis of ensemble learning. The complementarity of sub-size pathology image classifiers when machine performance is insufficient is explored in this experimental platform. We choose seven classical machine learning classifiers and four deep learning classifiers for classification experiments on the GasHisSDB database. Among them, classical machine learning algorithms extract five different image virtual features to match multiple classifier algorithms. For deep learning, we choose three convolutional neural network classifiers. In addition, we also choose a novel Transformer-based classifier. The experimental platform, in which a large number of classical machine learning and deep learning methods are performed, demonstrates that there are differences in the performance of different classifiers on GasHisSDB. Classical machine learning models exist for classifiers that classify Abnormal categories very well, while classifiers that excel in classifying Normal categories also exist. Deep learning models also exist with multiple models that can be complementarity. Suitable classifiers are selected for ensemble learning, when machine performance is insufficient. This experimental platform demonstrates that multiple classifiers are indeed complementarity and can improve the efficiency of ensemble learning. This can better assist doctors in diagnosis, improve the detection of gastric cancer, and increase the cure rate.

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