论文标题

Bioblox 2.5D-开发基于蛋白质对接的教育游戏

Bioblox 2.5D -- Developing an Educational Game Based on Protein Docking

论文作者

Leymarie, Frederic Fol, Latham, William, Salimbeni, Guido, Islam, Suhail A., Reynolds, Christopher, Cook, Charlie, Suarez, Luis Armas, Leinfellner, Richard, Sternberg, Michael J. E.

论文摘要

我们介绍了Bioblox2-5D的开发过程,这是一种针对青少年的教育生物学游戏。游戏内容是指蛋白质对接,旨在改善有关分子形状复杂性,电荷在分子对接中的作用以及计算结合亲和力的评分功能的学习。我们开发了该游戏,这是Goldsmiths,伦敦大学的计算部门与伦敦帝国学院的结构生物信息学集团之间合作的一部分。 Imperial的团队提供了内容要求,并验证了游戏中采用的技术解决方案。 Goldsmiths的团队将内容要求设计为一个有趣而刺激的教育益智游戏,以支持教学并激励学生参与生物学。我们说明了游戏设计选择,我们应用于完成所需学习成果的妥协和解决方案。本文旨在说明在生物学学生教育游戏开发的背景下,有用的见解和灵感。

We present the development process of Bioblox2-5D, an educational biology game aimed at teenagers. The game content refers to protein docking and aims to improve learning about molecular shape complexity, the roles of charges in molecular docking and the scoring function to calculate binding affinity. We developed the game as part of a collaboration between the Computing Department at Goldsmiths, University of London, and the Structural Bioinformatics group at Imperial College London. The team at Imperial provided the content requirements and validated the technical solution adopted in the game. The team at Goldsmiths designed and implemented the content requirements into a fun and stimulating educational puzzle game that supports teaching and motivates students to engage with biology. We illustrate the game design choices, the compromises and solutions that we applied to accomplish the desired learning outcomes. This paper aims to illustrate useful insights and inspirations in the context of educational game development for biology students.

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