论文标题
膜夹杂物之间的远距离相互作用：电场诱导成对电势的巨型扩增
Long-range interactions between membrane inclusions: Electric field induced giant amplification of the pairwise potential
论文作者
论文摘要
这项工作的目的是重新审视膜夹杂物之间相互作用的现象学理论，该理论是由膜波动介导的。我们考虑了夹杂物以大于其特征大小的距离分离的情况。在我们的宏观方法中，这种夹杂物的物理性质并不是必不可少的，但是我们始终考虑到这种包含的两个原型：蛋白质和RNA大分子。由于相互作用是由膜波动驱动的，以及包含物与膜之间的耦合，因此可以通过影响这些因素的外部动作来改变相互作用的潜力。作为这种外部动作的一个例子，我们考虑了电场。在外部电场（DC或AC）下，我们提出了具有偶极矩（大多数蛋白质大分子就是这种情况）和膜之间的新偶联机制。我们发现，最出乎意料的是，新的耦合机制产生了夹杂物的成对潜力的巨大增强。该结果为有目的的相互作用能量以及测试我们文章中规定的理论打开了一种方法。
The aim of this work is to revisit the phenomenological theory of the interaction between membrane inclusions, mediated by the membrane fluctuations. We consider the case where the inclusions are separated by distances larger than their characteristic size. Within our macroscopic approach a physical nature of such inclusions is not essential, however we have always in mind two prototypes of such inclusions: proteins and RNA macromolecules. Because the interaction is driven by the membrane fluctuations, and the coupling between inclusions and the membrane, it is possible to change the interaction potential by external actions affecting these factors. As an example of such external action we consider an electric field. Under external electric field (both dc or ac), we propose a new coupling mechanism between inclusions possessing dipole moments (as it is the case for most protein macromolecules) and the membrane. We found, quite unexpected and presumably for the first time, that the new coupling mechanism yields to giant enhancement of the pairwise potential of the inclusions. This result opens up a way to handle purposefully the interaction energy, and as well to test of the theory set forth in our article.
