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Entity Resolution suffers from quadratic time complexity. To increase its time efficiency, three kinds of filtering techniques are typically used for restricting its search space: (i) blocking workflows, which group together entity profiles with identical or similar signatures, (ii) string similarity join algorithms, which quickly detect entities more similar than a threshold, and (iii) nearest-neighbor methods, which convert every entity profile into a vector and quickly detect the closest entities according to the specified distance function. Numerous methods have been proposed for each type, but the literature lacks a comparative analysis of their relative performance. As we show in this work, this is a non-trivial task, due to the significant impact of configuration parameters on the performance of each filtering technique. We perform the first systematic experimental study that investigates the relative performance of the main methods per type over 10 real-world datasets. For each method, we consider a plethora of parameter configurations, optimizing it with respect to recall and precision. For each dataset, we consider both schema-agnostic and schema-based settings. The experimental results provide novel insights into the effectiveness and time efficiency of the considered techniques, demonstrating the superiority of blocking workflows and string similarity joins.