论文标题
使用浅景深的虚拟光学切片和层析成像的方法
A method for virtual optical sectioning and tomography utilizing shallow depth of field
论文作者
论文摘要
提出了一种方法，用于从平面传输图像中对物体内部结构进行高分辨率的三维重建。所描述的方法原则上可以与任何形式的辐射或物质波一起使用，只要景深小于样品的厚度。该方法的物理光学基础已阐明，并详细介绍了重建算法。一个模拟示例演示了该方法在逼真的辐射剂量和空间分辨率约束下应用于纳米颗粒的三维电子传输成像。可以预见，该方法可用于高分辨率透射电子显微镜，软X射线显微镜，超声成像和其他区域。
A method is proposed for high-resolution, three-dimensional reconstruction of internal structure of objects from planar transmission images. The described approach can be used with any form of radiation or matter waves, in principle, provided that the depth of field is smaller than the thickness of the sample. The physical optics basis for the method is elucidated and the reconstruction algorithm is presented in detail. A simulated example demonstrates an application of the method to three-dimensional electron transmission imaging of a nanoparticle under realistic radiation dose and spatial resolution constraints. It is envisaged that the method can be applicable in high-resolution transmission electron microscopy, soft X-ray microscopy, ultrasound imaging and other areas.
