论文标题
DNA在差溶剂中熔化
DNA melting in poor solvent
论文作者
论文摘要
使用简单的立方晶格上的修剪和富集的Rosenbluth方法研究了差溶剂中双链DNA的熔融相图。随着溶剂质量从良好变为差，熔化温度发生了非单调的变化。一阶熔化过渡（如良好的溶剂）让位于连续过渡，然后进一步扩大过渡，其中顺序参数平稳地变为零，以获得足够差的溶剂。熔融行为的这种变化伴随着沿熔融曲线的临界指数不断变化，暗示了熔化过渡的非宇宙性质。此外，我们表明，仅通过改变溶剂质量就可以实现未结合的阶段。重要的是，我们的结果依赖于实验发现。
The melting phase diagram of a double-stranded DNA in poor solvent is studied using the pruned and enriched Rosenbluth method on a simple cubic lattice. As the solvent quality is changed from good to poor, there is a non-monotonic change in the melting temperature. First-order melting transition, as in good solvent, gives way to continuous transition and then to further broadened transitions where the order parameter smoothly becomes zero for sufficiently poor solvent. This change in the melting behavior is accompanied by a continuously varying critical exponent along the melting curve, hinting at a non-universal nature of the melting transition. Further, we show that an unbound phase can be achieved just by changing the solvent quality. Importantly, our results conform to the experimental findings qualitatively.
