论文标题

智利的结直肠癌趋势:一个具有明显社会经济不平等明显的拉丁美洲国家

Colorectal cancer trends in Chile: a Latin-American country with marked socioeconomic inequities

论文作者

Mondschein, Susana, Subiabre, Felipe, Yankovic, Natalia, Estay, Camila, Von Mühlenbrock, Christian, Berger, Zoltan

论文摘要

结直肠癌(CRC)是世界上第三大常见的恶性疾病。在某些拥有既定筛查计划的国家,其发病率和死亡率也有所下降,生存率也有所改善。目的:为了获得有关智利CRC流行病学的可靠数据,我们分析了过去十年中的趋势以及可观察因素对生存的影响,包括CRC治疗访问(GES计划)的明确保证。 使用了卫生部和国家统计研究所发布的公开数据。数据是从死亡率和医院出院登记处获得的,从而使个人的随访。计算了原油和年龄标准化的发病率和死亡率,并通过构建Kaplan-Meier曲线来研究个体生存。最后,建立了COX统计模型,以估计可观察因素的影响。

Colorectal cancer (CRC) is the third most frequent malignant disease in the world. In some countries with established screening programs, its incidence and mortality have decreased, and survival has improved. AIMS: To obtain reliable data about the epidemiology of CRC in Chile, we analyzed the trends in the last ten years and the influence of observable factors on survival, including explicit guarantees in CRC treatment access (GES program). Publicly available data published by the Health Ministry and National Institute of Statistics were used. Data were obtained from registries of mortality and hospital discharges, making follow-up of the individuals possible. Crude and age-standardized incidence and mortality rates were calculated, and individual survival was studied by constructing Kaplan-Meier curves. Finally, a Cox statistical model was established to estimate the impact of the observable factors.

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