论文标题

统一的K空间理论的光学相干断层扫描理论

Unified k-space theory of optical coherence tomography

论文作者

Zhou, Kevin C., Qian, Ruobing, Dhalla, Al-Hafeez, Farsiu, Sina, Izatt, Joseph A.

论文摘要

我们提出了光学相干断层扫描(OCT)的一般理论,该理论综合了在共同的3D K-Space框架下OCT的基本概念和实现。该分析的核心是傅立叶衍射定理,该定理将样品和平面波之间的相干相互作用与样品的3D K空间表示中的Ewald球相关联。虽然通常在K空间中分析OCT的轴向维度,但我们表明,包含完全3D K空间形式主义可以解释几乎所有基本物理现象或OCT的属性,包括对比机制,分辨率,分散,差异,畸变,焦点深度和斑点。该理论还统一了衍射断层扫描,共聚焦显微镜,点扫描OCT,线场OCT,全场外OCT,Bessel-Beam OCT,经透明OCT,干涉合成光圈显微镜(ISAM)和光学相干性折射术(OCRT)等。我们的统一理论不仅可以清楚地了解现有技术,而且还建议新的研究方向继续前进OCT领域。

We present a general theory of optical coherence tomography (OCT), which synthesizes the fundamental concepts and implementations of OCT under a common 3D k-space framework. At the heart of this analysis is the Fourier diffraction theorem, which relates the coherent interaction between a sample and plane wave to the Ewald sphere in the 3D k-space representation of the sample. While only the axial dimension of OCT is typically analyzed in k-space, we show that embracing a fully 3D k-space formalism allows explanation of nearly every fundamental physical phenomenon or property of OCT, including contrast mechanism, resolution, dispersion, aberration, limited depth of focus, and speckle. The theory also unifies diffraction tomography, confocal microscopy, point-scanning OCT, line-field OCT, full-field OCT, Bessel-beam OCT, transillumination OCT, interferometric synthetic aperture microscopy (ISAM), and optical coherence refraction tomography (OCRT), among others. Our unified theory not only enables clear understanding of existing techniques, but also suggests new research directions to continue advancing the field of OCT.

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