论文标题
用圆极化光的癌症鉴定的角度优化
Angular optimization for cancer identification with circularly polarized light
论文作者
论文摘要
从生物组织中散射的圆极化光的去极化取决于细胞核的结构变化,这可以为区分隐藏在健康组织中的癌症组织提供有价值的信息。在这项研究中,我们使用圆形极化光的散射来实验验证了癌症鉴定的可能性。我们研究了从切片的生物组织中散射的光的极化,并具有各种光学构型。观察到了从癌性和健康组织分散的光的圆形极化之间的显着差异,这足以区分癌性区域。沿沿着健康和癌变部位的区域进行的扫描实验表明,循环极化程度的阶梯状行为,对应于组织状态,无论是癌性还是正常。倾斜和垂直的发生率诱导了不同的分辨率来鉴定癌组织,这表明可以根据分辨率的优先级选择光学布置。
Depolarization of circularly polarized light scattered from biological tissues depends on structural changes in cell nuclei, which can provide valuable information for differentiating cancer tissues concealed in healthy tissues. In this study, we experimentally verified the possibility of cancer identification using scattering of circularly polarized light. We investigated the polarization of light scattered from a sliced biological tissue with various optical configurations. A significant difference between circular polarizations of light scattered from cancerous and healthy tissues is observed, which is sufficient to distinguish a cancerous region. The line-scanning experiments along a region incorporating healthy and cancerous parts indicate step-like behaviors in the degree of circular polarization corresponding to the state of tissues, whether cancerous or normal. An oblique and perpendicular incidence induces different resolutions for identifying cancerous tissues, which indicates that the optical arrangement can be selected according to the priority of resolution.