论文标题

多元素相关生物材料系统中的区域分区化

Regional compartmentalization in multienzyme-related biomaterials system

论文作者

Xi, Zhexu

论文摘要

多烯酶级联反应被广泛使用,因为它们可以从简单的原材料中产生增值生物材料和生物介绍。但是,如何促进多元素系统的催化效率和协同作用被证明是一个挑战性的点。最近的发现反复强调了组装的多元素复合物的策略或形成亚细胞隔室进行空间优化的策略。这个高度有序且可调的组织有助于各种生化过程。该论文主要集中于分析和进步,在这种级联的策略中,同时在体内和体外对自然或人工生化反应的区域隔室的可行性。

Multienzyme cascaded reactions are widely utilized because they can generate value-added biomaterials and biodevices from simple raw materials. However, how to promote the catalytic efficiency and synergistic effect of the multienzyme system is proved to be a challengeable point. Recent discovery repeatedly emphasized the strategy of assembled multienzyme complexes or forming subcellular compartments for spacial optimization. This highly ordered and tunable organization contributes to various biochemical processes. This dissertation focuses mainly on analysis and progresses in this cascaded strategy, regarding the feasibility of regional compartments for natural or artificial biochemical reactions in vivo and vitro, simultaneously.

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