论文标题
开放式准系统系统：进化适应的新方法
Open Quasispecies Systems: New Approach to Evolutionary Adaptation
论文作者
论文摘要
考虑适应性景观和突变矩阵进化适应的数学模型，以此作为对种群变化的反应。作为基础，我们使用开放的准菜模型，该模型已修改为包括显式死亡流。我们假设突变和选择过程的进化参数以最大化系统平均适应性的方式有所不同。从这个角度来看，Fisher的自然选择定理正在重新考虑和讨论。另一个假设是系统动力学具有两个重要的时间尺度。根据我们的中心假设，主要的进化转变发生在相应的动力学系统的稳态中，因此进化时间比内部动力学之一要慢得多。对于准特性系统的特定情况，我们展示了我们的前提如何形成健身景观适应过程。
Consider a mathematical model of evolutionary adaptation of fitness landscape and mutation matrix as a reaction to population changes. As a basis, we use an open quasispecies model, which is modified to include explicit death flow. We assume that evolutionary parameters of mutation and selection processes vary in a way to maximize the mean fitness of the system. From this standpoint, Fisher's theorem of natural selection is being rethought and discussed. Another assumption is that system dynamics has two significant timescales. According to our central hypothesis, major evolutionary transitions happen in the steady-state of the corresponding dynamical system, so the evolutionary time is much slower than the one of internal dynamics. For the specific cases of quasispecies systems, we show how our premises form the fitness landscape adaptation process.
