论文标题
病毒传播的数学模型
A Mathematical Model For the Spread of a Virus
论文作者
论文摘要
本文描述了病毒通过给定大小的孤立人群传播的数学模型。该模型使用三个颜色编码的成分,称为分子(红色用于感染且仍然具有传染性;绿色用于感染,但不再具有传染性;未感染的蓝色)。回想起来,该模型是Kermac和McKendrick(1927)的著名爵士模型的数字类似物。在我们的RGB模型中,累积感染的数量经历了三个阶段,从非常低的水平开始,然后转变为快速增长的过渡坡道,并以最终值的平稳性结束。 Consequently, the differential change or growth rate begins at 0, rises to a peak corresponding to the maximum slope of the transition ramp, and then falls back to 0. The properties of these time variations, including the slope, duration, and height of the transition ramp, and the width and height of the infection rate, depend on a single parameter - the time that a red molecule is contagious divided by the average time between collisions of the molecules.各种时间里程碑,包括过渡坡道的起始时间,累积的感染数量获得其最大斜率的时间,以及感染率的峰值位置取决于人口的大小,而除了传染性的寿命比。这些数量的显式公式被得出并汇总。最后,添加了附录E来描述疫苗接种的影响。
This paper describes a mathematical model for the spread of a virus through an isolated population of a given size. The model uses three, color-coded components, called molecules (red for infected and still contagious; green for infected, but no longer contagious; and blue for uninfected). In retrospect, the model turns out to be a digital analogue for the well-known SIR model of Kermac and McKendrick (1927). In our RGB model, the number of accumulated infections goes through three phases, beginning at a very low level, then changing to a transition ramp of rapid growth, and ending in a plateau of final values. Consequently, the differential change or growth rate begins at 0, rises to a peak corresponding to the maximum slope of the transition ramp, and then falls back to 0. The properties of these time variations, including the slope, duration, and height of the transition ramp, and the width and height of the infection rate, depend on a single parameter - the time that a red molecule is contagious divided by the average time between collisions of the molecules. Various temporal milestones, including the starting time of the transition ramp, the time that the accumulating number of infections obtains its maximum slope, and the location of the peak of the infection rate depend on the size of the population in addition to the contagious lifetime ratio. Explicit formulas for these quantities are derived and summarized. Finally, Appendix E has been added to describe the effect of vaccinations.