论文标题
GASNET:COVID-19病变细分的弱监督框架
GASNet: Weakly-supervised Framework for COVID-19 Lesion Segmentation
论文作者
论文摘要
胸部CT体积中感染区域的分割对于进一步诊断和治疗COVID-19患者具有重要意义。由于病变的复杂形状和各种外观,通常需要大量的体素级标记样品来训练病变分割网络,这是开发基于深度学习的医学图像分割算法的主要瓶颈。在本文中,我们提出了一个弱监督的病变分割框架,通过将生成性对抗训练过程嵌入分割网络,称为GASNET。优化了GASNET,以通过分段器将COVID-19 CT的病变区域进行分割,并用发电机的正常外观代替异常外观,因此恢复的CT体积与鉴别器的健康CT量无法区分。 GASNET受许多健康和共同199受试者的胸部CT体积监督,没有体素级注释。在三个公共数据库上的实验表明,当使用一个素级标记的样品的少量时,GASNET的性能与对数十个体素级标记的样品进行训练的完全监督分割算法相当。
Segmentation of infected areas in chest CT volumes is of great significance for further diagnosis and treatment of COVID-19 patients. Due to the complex shapes and varied appearances of lesions, a large number of voxel-level labeled samples are generally required to train a lesion segmentation network, which is a main bottleneck for developing deep learning based medical image segmentation algorithms. In this paper, we propose a weakly-supervised lesion segmentation framework by embedding the Generative Adversarial training process into the Segmentation Network, which is called GASNet. GASNet is optimized to segment the lesion areas of a COVID-19 CT by the segmenter, and to replace the abnormal appearance with a generated normal appearance by the generator, so that the restored CT volumes are indistinguishable from healthy CT volumes by the discriminator. GASNet is supervised by chest CT volumes of many healthy and COVID-19 subjects without voxel-level annotations. Experiments on three public databases show that when using as few as one voxel-level labeled sample, the performance of GASNet is comparable to fully-supervised segmentation algorithms trained on dozens of voxel-level labeled samples.