论文标题
基因组学应用类别理论 - 一项倡议
Applied Category Theory for Genomics -- An Initiative
论文作者
论文摘要
地球上所有生命的最终秘密都隐藏在其基因组中 - 全部DNA序列。目前，我们知道许多生物的整个基因组序列，而我们对系统水平上基因组结构的理解仍然是基本的。应用类别理论开辟了一种有希望的方式，可以整合基因组学中巨大的异质信息，促进我们对基因组组织的了解，并为我们提供对自己基因组的深刻而整体的看法。在这项工作中，我们解释了为什么应用类别理论带有如此希望，我们继续展示它如何实际做到这一点，尽管在婴儿步骤中。手稿打算对数学家和生物学家都可以理解，因此，双方都不需要先验知识。
The ultimate secret of all lives on earth is hidden in their genomes -- a totality of DNA sequences. We currently know the whole genome sequence of many organisms, while our understanding of the genome architecture on a systematic level remains rudimentary. Applied category theory opens a promising way to integrate the humongous amount of heterogeneous informations in genomics, to advance our knowledge regarding genome organization, and to provide us with a deep and holistic view of our own genomes. In this work we explain why applied category theory carries such a hope, and we move on to show how it could actually do so, albeit in baby steps. The manuscript intends to be readable to both mathematicians and biologists, therefore no prior knowledge is required from either side.
