论文标题
估计二项式比例的倒数
Estimating the reciprocal of a binomial proportion
论文作者
论文摘要
作为二项式分布的经典参数,由于其广泛的应用范围,在文献中对二项式比例进行了很好的研究。相反,二项式比例的倒数(也称为反比例)通常被忽略,尽管它在包括临床研究和随机抽样在内的各个领域也起着重要作用。反比例的最大似然估计量遭受了零事件问题的影响,并且为了克服它,文献中已经开发了替代方法。然而,几乎没有工作解决现有估计器的最佳性以及其实际性能比较。受到这一点的启发,我们建议通过为收缩估计量家族中的逆比例开发最佳估计量来进一步推进文献。我们进一步得出了不同设置下最佳收缩参数的显式和近似公式。仿真研究表明,在大多数实际情况下,我们的新估计器的性能要比现有竞争对手或现有竞争对手更好。最后,为了说明我们的新方法的有用性,我们还重新审视了Covid-19数据的最新荟萃分析,用于评估冠状病毒感染的物理距离的相对风险,其中七项研究遇到了零事实问题。
As a classic parameter from the binomial distribution, the binomial proportion has been well studied in the literature owing to its wide range of applications. In contrast, the reciprocal of the binomial proportion, also known as the inverse proportion, is often overlooked, even though it also plays an important role in various fields including clinical studies and random sampling. The maximum likelihood estimator of the inverse proportion suffers from the zero-event problem, and to overcome it, alternative methods have been developed in the literature. Nevertheless, there is little work addressing the optimality of the existing estimators, as well as their practical performance comparison. Inspired by this, we propose to further advance the literature by developing an optimal estimator for the inverse proportion in a family of shrinkage estimators. We further derive the explicit and approximate formulas for the optimal shrinkage parameter under different settings. Simulation studies show that the performance of our new estimator performs better than, or as well as, the existing competitors in most practical settings. Finally, to illustrate the usefulness of our new method, we also revisit a recent meta-analysis on COVID-19 data for assessing the relative risks of physical distancing on the infection of coronavirus, in which six out of seven studies encounter the zero-event problem.