论文标题
修改的正交匹配追求,用于构建稀疏概率布尔网络
A Modified Orthogonal Matching Pursuit for Construction of Sparse Probabilistic Boolean Networks
论文作者
论文摘要
概率布尔网络在基因调节网络的建模和控制中发挥了非凡的作用。在本文中,我们考虑了从规定的过渡概率矩阵中构建稀疏概率布尔网络的逆问题。我们提出了一种修改的正交匹配追求,以解决逆问题。我们提供了一些条件,在这些条件下,所提出的算法可以恢复稀疏的概率布尔网络。我们还报告了一些数值结果,以说明所提出算法的有效性。
Probabilistic Boolean Networks play a remarkable role in the modelling and control of gene regulatory networks. In this paper, we consider the inverse problem of constructing a sparse probabilistic Boolean network from the prescribed transition probability matrix. We propose a modified orthogonal matching pursuit for solving the inverse problem. We provide some conditions under which the proposed algorithm can recover a sparse probabilistic Boolean network. We also report some numerical results to illustrate the effectiveness of the proposed algorithm.