学术文献库

Objective: This pilot study was done to evaluate the capability of a prototype low cost blue light emitting diode (LED) phototherapy device in lowering bilirubin levels among healthy term infants diagnosed with indirect hyperbilirubinemia. Methods: Experimental study on term infants diagnosed with indirect hyperbilirubinemia in Ospital ng Makati from May 2016 to November 2016 who underwent phototherapy using the low cost blue LED phototherapy prototype. Results: After 24 hours of phototherapy under the prototype LED phototherapy unit, 16% of the total patients completed treatment as they were already classified in the low risk zone, and another 36% of patients completed treatment after 48 hours. The total bilirubin significantly decreased from baseline bilirubin levels after 24 hours by 16.5% (p = 0.0001). The mean percentage of change of bilirubin reduced after 48 hours of 29.9% was also significant. The proportion of subjects in the high risk zone during baseline to 24th hour went down significantly from 80% to 28% (p = 0.0003), while comparing baseline to 48th hour, the percentage of high risk zone went down from 80% to 9.5% (p = 0.0001). No subjects were reported to have rebound hyperbilirubinemia after discontinuation of phototherapy treatment under the LED prototype. No patient experienced any complication while on phototherapy treatment. Conclusion: The prototype low cost blue light emitting diode (LED) phototherapy was able to lower total serum bilirubin among healthy term infants with indirect hyperbilirubinemia and was safe to use.