论文标题

主机到宿主空降传输作为基于科学的社会距离指南的多相流问题

Host-to-Host Airborne Transmission As a Multiphase Flow Problem For Science-Based Social Distance Guidelines

论文作者

Balachandar, S., Zaleski, S., Soldati, A., Ahmadi, G., Bourouiba, L.

论文摘要

Covid-19的大流行已经明显地证明了在人类传播的背景下,发展与病原体液滴的产生,运输和吸入有关的基本知识以及随后作为空气颗粒或气溶胶的可能命运是多么重要。同样越来越清楚的是,空中传播是疾病快速传播的重要贡献者。在本文中,我们通过呼气讨论了液滴产生的过程,它们的潜在转化通过蒸发,通过呼出的泡芙长途运输和环境空气湍流在长途运输,以及接收宿主作为互连的多变流动过程的最终吸入。基于对相关物理过程的理论分析,提出了液滴/气溶胶浓度时间演变的简单模型。建模框架以及详细的实验和模拟可以用于研究涉及呼吸,说话,咳嗽和打喷嚏的各种情况,以及在许多环境条件下,例如潮湿或干燥的气氛,受到约束或开放环境。尽管关于蒸发和结合病毒的持续性的物理学仍然存在许多问题,但很明显,有了对病毒传播的基本流动物理学的更可靠的理解,人们可以在设计特定病例的社会疏远和感染控制指南方面为改进的方法奠定基础。

COVID-19 pandemic has strikingly demonstrated how important it is to develop fundamental knowledge related to generation, transport and inhalation of pathogen-laden droplets and their subsequent possible fate as airborne particles, or aerosols, in the context of human to human transmission. It is also increasingly clear that airborne transmission is an important contributor to rapid spreading of the disease. In this paper, we discuss the processes of droplet generation by exhalation, their potential transformation into airborne particles by evaporation, transport over long distances by the exhaled puff and by ambient air turbulence, and final inhalation by the receiving host as interconnected multiphase flow processes. A simple model for the time evolution of droplet/aerosol concentration is presented based on a theoretical analysis of the relevant physical processes. The modeling framework along with detailed experiments and simulations can be used to study a wide variety of scenarios involving breathing, talking, coughing and sneezing and in a number of environmental conditions, as humid or dry atmosphere, confined or open environment. Although a number of questions remain open on the physics of evaporation and coupling with persistence of the virus, it is clear that with a more reliable understanding of the underlying flow physics of virus transmission one can set the foundation for an improved methodology in designing case-specific social distancing and infection control guidelines.

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