论文标题

在7 t的大鼠MRI的实验开发和评估带有开槽的端环线圈的体积线圈

Experimental development and evaluation of a volume coil with slotted end-rings coil for rat MRI at 7 T

论文作者

Solis-Najera, S., Martin, R., Vazquez, F., Marrufo, O., Rodriguez, A. O.

论文摘要

开发了带有平方槽末端环的体积线圈,以提高在7 t时大鼠大脑成像的灵敏度。低通用病例的高腔谐振器的原理,并使用生物武器定律来得出线圈敏感性的理论表达。开槽的环谐振器比具有相似尺寸的标准鸟笼线圈显示出理论上的2.22倍改进。对电磁场进行了数值研究,并为我们的线圈进行了特定的吸收率,以及装有盐水填充圆柱形幻影和大鼠数字大脑的鸟笼线圈。无论电磁模拟中使用的载荷如何,都可以观察到鸟笼上插槽体积线圈的信噪比(SNR)的改善。特定的吸收率仿真显示了数字大脑的重要减少,而盐溶液幻影的值非常相似。幻影和大鼠的大脑图像是在7 t时获得的,以证明线圈设计的生存能力。我们的线圈设计的实验噪声图是具有相似尺寸的标准鸟笼的四倍,女巫的实验SNR增加了30%。在理论,数值和实验灵敏度值之间存在显着的一致性,这都表明,可以使用开槽的末端环可以改善小啮齿动物的MR成像的线圈性能。

A volume coil with squared slots-end ring was developed to attain improved sensitivity for imaging of rat's brain at 7 T. The principles of the high cavity resonator for the low-pass case and the law of Biot-Savart were used to derive a theoretical expression of the coil sensitivity. The slotted-end ring resonator showed a theoretical 2.22-fold improvement over the standard birdcage coil with similar dimensions. Numerical studies were carried out for the electromagnetic fields and specific absorption rates for our coil and a birdcage coil loaded with a saline-filled cylindrical phantom and a digital brain of a rat. An improvement of the signal-to-noise ratio (SNR) can be observed for the slotted volume coil over the birdcage regardless of the load used in the electromagnetic simulations. The specific absorption rate simulations show an important decrement for the digital brain and quite similar values with the saline solution phantom. Phantom and rat's brain images were acquired at 7 T to prove the viability of the coil design. The experimental noise figure of our coil design was four times less than the standard birdcage with similar dimensions, witch showed a 30% increase in experimental SNR. There is remarkable agreement among the theoretical, numerical and experimental sensitivity values, which all demonstrate that the coil performance for MR imaging of small rodents can be improved using slotted end-rings.

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