论文标题
多发性硬化症中同时全脑和病变分割的纵向方法
A Longitudinal Method for Simultaneous Whole-Brain and Lesion Segmentation in Multiple Sclerosis
论文作者
论文摘要
在本文中，我们提出了一种新的方法，用于分割患有多发性硬化症患者的纵向脑MRI扫描。该方法建立在现有的同时全脑和病变分割的现有横截面方法的基础上，引入了特定于主题的潜在变量，以鼓励纵向扫描之间的时间一致性。它通常是非常适用的，因为它没有对扫描仪，MRI协议或纵向随访扫描的数量和时机做出任何以前的假设。在三个纵向数据集上进行的初步实验表明，所提出的方法会产生更可靠的分割，并检测到疾病的影响比基于横截面方法更好。
In this paper we propose a novel method for the segmentation of longitudinal brain MRI scans of patients suffering from Multiple Sclerosis. The method builds upon an existing cross-sectional method for simultaneous whole-brain and lesion segmentation, introducing subject-specific latent variables to encourage temporal consistency between longitudinal scans. It is very generally applicable, as it does not make any prior assumptions on the scanner, the MRI protocol, or the number and timing of longitudinal follow-up scans. Preliminary experiments on three longitudinal datasets indicate that the proposed method produces more reliable segmentations and detects disease effects better than the cross-sectional method it is based upon.
