论文标题
键图统一化学计量分析和热力学
Bond Graphs Unify Stoichiometric Analysis and Thermodynamics
论文作者
论文摘要
全细胞建模受到一般自然定律的限制,尤其是热力学定律。本文展示了如何使用网络热力学的粘结图方法将一种多产的信息来源,生物分子系统的化学计量模型与热力学原理集成在一起。
Whole-cell modelling is constrained by the laws of nature in general and the laws of thermodynamics in particular. This paper shows how one prolific source of information, stoichiometric models of biomolecular systems, can be integrated with thermodynamic principles using the bond graph approach to network thermodynamics.