论文标题
自适应玻璃波兰传感器无视野OCT，用于广泛视野的高分辨率视网膜成像
Adaptive-glasses wavefront sensorless full-field OCT for high-resolution retinal imaging over a wide field-of-view
论文作者
论文摘要
通过将光学相干断层扫描（OCT）和自适应光学（AO）相结合，可以实现体内视网膜成像中最高的三维（3D）分辨率。但是，这种组合带来了重要的局限性，例如较小的视野和复杂的，繁琐的系统，从而阻止了该技术从研究实验室到诊所的转换。在这封信中，我们介绍了一种方法，该方法通过在眼前使用多传动器自适应镜头来避免这些局限性，我们将其称为Adaptive-Glasses Wavebront Sensor无传感器方法。我们在紧凑的全场OCT（FFOCT）视网膜成像器上实现了这种方法，而无需增加其足迹或光学复杂性。通过自适应玻璃的方法校正眼畸变，增加了FFOCT信噪比的比率，使我们能够以5°$ \ times $ \ times $ 5°$ 5°的视野图像不同的视网膜层成像不同的视网膜层，而没有明显的Anisoplanatism。
The highest three-dimensional (3D) resolution possible in in-vivo retinal imaging is achieved by combining optical coherence tomography (OCT) and adaptive optics (AO). However, this combination brings important limitations, such as small field-of-view and complex, cumbersome systems, preventing so far the translation of this technology from the research lab to clinics. In this Letter, we introduce an approach that avoids these limitations by using a multi-actuator adaptive lens just in front of the eye, in a technique we call the adaptive-glasses wavefront sensorless approach. We implemented this approach on our compact full-field OCT (FFOCT) retinal imager without increasing its footprint or optical complexity. The correction of ocular aberrations through the adaptive-glasses approach increased the FFOCT signal-to-noise ratio and enabled us to image different retinal layers with a 3D cellular resolution in a 5° $\times$ 5° field-of-view, without apparent anisoplanatism.
