论文标题
由多种草甘膦研究激发的重复致癌性生物测定的Tukey型趋势测试
A Tukey type trend test for repeated carcinogenicity bioassays, motivated by multiple glyphosate studies
论文作者
论文摘要
在过去的二十年中，出现了简单和复杂的随机设计的同时推断，尤其是比例作为终点的重大进展。这包括：i）新的Tukey趋势测试方法，ii）二项式比例的多个对比度测试，iii）多重K估计的多个对比度测试，以及单侧推断的添加1近似值。该报告的重点是新的Tukey型趋势测试，以评估重复的长期致癌性生物测定，这是由多种草甘膦研究激发的。注意，这里不是为了评估草甘膦及其争议的目的。通过Cran-ackages tukeyTrend，McPan，MultComp，实际数据分析是一种直接的。
In the last two decades, significant methodological progress to the simultaneous inference of simple and complex randomized designs, particularly proportions as endpoints, occurred. This includes: i) the new Tukey trend test approach, ii) multiple contrast tests for binomial proportions, iii) multiple contrast tests for poly-k estimates, and Add-1 approximation for one-sided inference. This report focus on a new Tukey type trend test to evaluate repeated long-term carcinogenicity bioassays which was motivated by multiple glyphosate studies. Notice, it is not the aim here to contribute to the evaluation of Glyphosate and its controversies. By means of the CRAN-packages tukeytrend, MCPAN, multcomp the real data analysis is straightforward possible.
