论文标题
主动nematics中的多尺度微管动力学
Multiscale Microtubule Dynamics in Active Nematics
论文作者
论文摘要
在基于微管的主动神经化学中，微管束的运动驱动的扩展运动能力混乱的大规模动力学。我们在孤立的束和致密的活性列中量化了丝间滑动运动。孤立的微管对的延伸速度与分子运动步进速度相当。相比之下，密集的2D活性神经中的净延伸明显较慢。丝间滑速左右分布在平均值上，细丝均表现出收缩和扩展相对运动。这些测量值强调了将隔离束的扩展速率连接到密集的2D活动列中存在的多运动和多丝相互作用的挑战。他们还提供了对构建多尺度模型至关重要的定量数据。
In microtubule-based active nematics, motor-driven extensile motion of microtubule bundles powers chaotic large-scale dynamics. We quantify the interfilament sliding motion both in isolated bundles and in a dense active nematic. The extension speed of an isolated microtubule pair is comparable to the molecular motor stepping speed. In contrast, the net extension in dense 2D active nematics is significantly slower; the interfilament sliding speeds are widely distributed about the average and the filaments exhibit both contractile and extensile relative motion. These measurements highlight the challenge of connecting the extension rate of isolated bundles to the multi-motor and multi-filament interactions present in a dense 2D active nematic. They also provide quantitative data that is essential for building multiscale models.
