论文标题
使用数值模拟对气溶胶传输和病毒暴露进行建模与在室内吸入SARS-COV-2传播有关的模拟
Modelling aerosol transport and virus exposure with numerical simulations in relation to SARS-CoV-2 transmission by inhalation indoors
论文作者
论文摘要
我们提供有关与假设的SARS-COV-2的气溶胶传播相关的气溶胶分散物理学的研究结果。我们利用基于物理的建模在不同级别的复杂性以及有关冠状病毒的文献来研究空气传播的可能性。先前的文献,即通过各种基于物理学的模型的0D-3D模拟以及理论计算,表明典型的语音和咳嗽量的大小范围是起源液滴(d <20microns)允许在空气中挥之不去的O(1H),以便吸入它们。与以前的文献一致,提供了关于大液滴的快速干燥过程的数值证据,最多是o(100microns)的液滴核/气溶胶。根据文献和公共媒体来源,我们提供了证据表明,被感染的个体可以通过大量吸入(例如O(100)。通过3D计算流体动力学(CFD)仿真,我们在通用环境中提供了距离O(10m)的气溶胶(d <20microns)的传输和稀释的示例。我们通过蒙特 - 卡洛建模在通用公共场所研究易感和感染的人。该模型解释了易感通过吸入积累的局部变化的气溶胶浓度水平。提出了引入的概念“暴露时间”,以补充传统的“安全距离”思维。我们表明,根据情况,接触O(100)气溶胶的暴露时间可能从O(1s)到O(1分钟),甚至可能取决于O(1H)。蒙特卡洛分析为不同公共室内环境中的暴露时间提供了明确的定量见解。
We provide research findings on the physics of aerosol dispersion relevant to the hypothesized aerosol transmission of SARS-CoV-2. We utilize physics-based modeling at different levels of complexity, and literature on coronaviruses, to investigate the possibility of airborne transmission. The previous literature, our 0D-3D simulations by various physics-based models, and theoretical calculations, indicate that the typical size range of speech and cough originated droplets (d < 20microns) allows lingering in the air for O(1h) so that they could be inhaled. Consistent with the previous literature, numerical evidence on the rapid drying process of even large droplets, up to sizes O(100microns), into droplet nuclei/aerosols is provided. Based on the literature and the public media sources, we provide evidence that the infected individuals could have been exposed to aerosols/droplet nuclei by inhaling them in significant numbers e.g. O(100). By 3D computational fluid dynamics (CFD) simulations, we give examples on the transport and dilution of aerosols (d<20microns) over distances O(10m) in generic environments. We study susceptible and infected individuals in generic public places by Monte-Carlo modeling. The model accounts for the locally varying aerosol concentration levels which the susceptible accumulate via inhalation. The introduced concept, 'exposure time' to virus containing aerosols is proposed to complement the traditional 'safety distance' thinking. We show that the exposure time to inhale O(100) aerosols could range from O(1s) to O(1min) or even to O(1h) depending on the situation. The Monte Carlo analysis provides clear quantitative insight to the exposure time in different public indoor environments.