论文标题
模拟激光诱导的视网膜热损伤，以根据激光安全标准进行非均匀辐照度轮廓及其评估
Simulation of laser induced retinal thermal injuries for non-uniform irradiance profiles and their evaluation according to the laser safety standard
论文作者
论文摘要
在可见的和近红外区域发射辐射的激光系统可能对人眼的视网膜有害。这可能导致由于光学机械，光热或光化学光组织相互作用而导致无法弥补的伤害。该研究的重点是用于模拟视网膜的热行为并预测损伤阈值值的光热相互作用。最重要的因素是视网膜上辐射的波长，暴露时间和辐照度。为了进行安全评估和分类，必须考虑激光安全标准IEC 60825-1：2014。这些评估基于排放限，取决于上述相同的因素。根据IEC 60825-1：2014，通过图像分析来处理不均匀的视网膜图像，该图像分析使用平均点大小。该平均大小是根据两个正交方向的辐照度曲线的程度计算得出的。与激光安全标准不同，计算机模型可以预测视网膜上辐照度概况的损伤阈值，而无需平均斑点尺寸。在这项调查中，研究了计算机模型预测的损伤阈值以及根据激光安全标准对分类进行了各种不均匀的视网膜图像。
Laser systems emitting radiation in the visible and near infrared region are potentially hazardous for the retina of the human eye. This can result in irreparable injuries due to photomechanical, photothermal or photochemical light-tissue interactions. This investigation focuses on the photothermal interaction for which a computer model is used to simulate the thermal behavior of the retina and to predict the injury threshold values. The most important factors are the wavelength of the radiation, the exposure time and the irradiance profile on the retina. For performing safety evaluations and classifications the laser safety standard IEC 60825-1:2014 has to be considered. These evaluations are based on emission limits which depend on the same above mentioned factors. According to the IEC 60825-1:2014, non-uniform retinal images are treated by an image analysis where an averaged spot size is used. This averaged size is calculated by the extent of the irradiance profile along two orthogonal directions. Unlike the laser safety standard, the computer model predicts the injury thresholds for an irradiance profile on the retina without averaging the spot size. In this investigation, a broad variety of non-uniform retinal images is investigated with regard to the injury thresholds predicted by the computer model and to the classifications according to the laser safety standard.
