论文标题
一种基于聚合物的技术，可从软隐形眼镜中去除污染物
A polymer-based technique to remove pollutants from soft contact lenses
论文作者
论文摘要
目的：展示一种清洁柔软隐形眼镜外表面清洁污染物的冲洗和摩擦方法的替代方法。该提出的技术称为聚合物污染物去除（POPPR）的聚合物，该技术利用聚二甲基硅氧烷（PDMS）的弹性特性通过非粘合剂的脱皮从隐形眼镜表面中物理去除污染物。 方法：使用POPPR方法对RR的控制方法评估了三种不同的设置剂与聚合物PDM的比率（1:30、1:40和1:50），并使用商业多功能透镜清洁解决方案进行了RR的控制方法。三种不同尺寸的模拟污染物：花粉（25-40μM），微粒（1-5μM）和纳米颗粒（5-10 nm）用于测试两种清洁方法的有效性。记录并评估从每个隐形眼镜中去除的污染物的分数。 结果：发现PDMS 1:40是使用POPPR方法清洁镜头的最佳比率。对于较大的颗粒（>10μm），在常规RR和提出的POPPR方法之间未观察到差异（P> 0.05）。然而，与RR方法相比，新的POPPR技术在去除小PM2.5颗粒（<2.5μm）方面，特别是对于Microbeads（P = 0.006）和纳米颗粒（P <0.001）而明显更好。 结论：概念验证的工作表明，清洁隐形眼镜的POPPR方法与较大颗粒（例如花粉）的常规清洁方法一样有效。 POPPR方法在去除包括微塑料和纳米颗粒在内的极细颗粒污染物方面更有效。该方法提供了一种潜在的更有效的清洁协议，可以增强隐形眼镜使用者的安全，健康和舒适性，尤其是那些居住在空气污染的地区的人。
Purpose: To demonstrate an alternative to the rinse and rub (RR) method for cleaning pollutants from the exterior surface of soft contact lenses. This proposed technique is termed Polymer on Polymer Pollutant Removal (PoPPR), which utilizes the elastic properties of polydimethylsiloxane (PDMS) to physically remove contaminants from contact lens surfaces through non-adhesive unpeeling. Methods: Three different ratios of setting agent to polymer PDMS (1:30, 1:40, and 1:50) were evaluated using the PoPPR method against the control method of RR with a commercial multi-purpose lens cleaning solution. Three simulated pollutants of different sizes: pollen (25-40 μm), microbeads (1-5 μm), and nanoparticles (5-10 nm), were used to test the effectiveness of both cleaning methods. The fraction of pollutants removed from each contact lens was recorded and evaluated for significance. Results: PDMS 1:40 was found to be the optimal ratio for lens cleaning using the PoPPR method. For larger particles (>10 μm), no difference was observed between conventional RR and proposed PoPPR method (p > 0.05). However, the new PoPPR technique was significantly better at removing small PM2.5 particles (<2.5 μm) compared to the RR method, specifically for microbeads (p = 0.006) and nanoparticles (p < 0.001). Conclusion: This proof-of-concept work demonstrates that the PoPPR method of cleaning contact lenses is as effective as the conventional cleaning method for larger particles such as pollen. The PoPPR method is more effective at removing extremely fine particulate pollutants, including microplastics and nanoparticles. This method offers a potentially more efficient cleaning protocol that could enhance the safety, health, and comfort of contact lens users, especially those living in regions with significant air pollution.
