论文标题
量子增强的刺激发射显微镜
Quantum-enhanced stimulated emission microscopy
论文作者
论文摘要
非线性光学显微镜技术已成为一组成功的生物成像工具。刺激的发射显微镜属于一小部分泵探针技术，这些技术可以对非荧光样品进行成像，而无需荧光标记。然而，它的灵敏度最终被探针束中的量子波动限制。我们提出并通过在强度切成症状的状态下制备探针脉冲来提出并实验实现限制刺激的发射显微镜。这项技术为成像没有可检测到的荧光的精致生物样品铺平了道路，其灵敏度超出了标准量子波动。
Nonlinear optical microscopy techniques have emerged as a set of successful tools for biological imaging. Stimulated emission microscopy belongs to a small subset of pump-probe techniques which can image non-fluorescent samples without requiring fluorescent labelling. However, its sensitivity has been shown to be ultimately limited by the quantum fluctuations in the probe beam. We propose and experimentally implement sub-shot-noise limited stimulated emission microscopy by preparing the probe pulse in an intensity-squeezed state. This technique paves the way for imaging delicate biological samples that have no detectable fluorescence with sensitivity beyond standard quantum fluctuations.
