论文标题
MOS $ _2 $纳米膜膜中单分子检测的微观传输分析
Microscopic Transport Analysis of Single Molecule Detection in MoS$_2$ Nanopore Membranes
论文作者
论文摘要
提出了对MOS2纳米苯纳米孔中单个生物分子的电子检测所涉及的各种电阻效应的微观物理分析。该分析取决于一种组合实验理论方法，其中，由于DNA和蛋白质分子通过孔隙的转运而沿二维（2D）膜的横向电子电流的变化与基于分子动力学（MD）和Boltzmann转运形式的模型计算进行比较，以评估毛白毛脑的传输。我们的分析指出了离子之间的自洽相互作用，孔边缘周围的载体和生物分子周围的载体强调了电解质浓度，孔径，纳米替宾几何形状的效果，但也强调了纳米替体对纳米核心对纳米敏感性的兴奋性极性，并同意检测到纳米核心的敏感性。
A microscopic physical analysis of the various resistive effects involved in the electronic detection of single biomolecules in a nanopore of a MoS2 nanoribbon is presented. The analysis relies on a combined experimental-theoretical approach, where the variations of the transverse electronic current along the two-dimensional (2D) membrane due to the translocation of DNA and proteins molecules through the pore are compared with model calculations based on molecular dynamics (MD) and Boltzmann transport formalism for evaluating the membrane conductance. Our analysis that points to a self-consistent interaction among ions, charge carriers around the pore rim and biomolecules, emphasizes the effects of the electrolyte concentration, pore size, nanoribbon geometry, but also the doping polarity of the nanoribbon on the electrical sensitivity of the nanopore in detecting biomolecules, which agrees well with the experimental data.
