论文标题

LU-NET:通过深度学习2D超声心动图的深度学习来提高左心室结构分割的鲁棒性的多任务网络

LU-Net: a multi-task network to improve the robustness of segmentation of left ventriclular structures by deep learning in 2D echocardiography

论文作者

Leclerc, Sarah, Smistad, Erik, Østvik, Andreas, Cervenansky, Frederic, Espinosa, Florian, Espeland, Torvald, Berg, Erik Andreas Rye, Grenier, Thomas, Lartizien, Carole, Jodoin, Pierre-Marc, Lovstakken, Lasse, Bernard, Olivier

论文摘要

心脏结构的分割是估计心脏量指数的基本步骤之一。此步骤仍在临床常规中半自动进行,因此容易出现在观察者间和观察者内变异性。最近的研究表明,深度学习有可能执行全自动分割。但是,目前的最佳解决方案仍然缺乏鲁棒性。在这项工作中,我们引入了一个端到端的多任务网络,旨在提高心脏细分的整体准确性,同时增强临床指数的估计并减少异常值的数量。在大型开放访问数据集上获得的结果表明,我们的方法的表现优于当前最佳性能深度学习解决方案,并实现了超过心外神经边界内观察者内变异性的总体细分精度,即平均平均绝对误差为1.5mm,Hausdorff距离为5.1mm,为5.1mm,为11%)。此外,我们证明我们的方法可以与末期末期和末期左心室体积的专家分析密切复制,平均相关性为0.96,平均绝对误差为7.6ml。关于左心室的射血分数,结果与平均相关系数为0.83,绝对平均误差为5.0%,产生的得分略低于观察者内部的分数。基于此观察结果,建议改进领域。

Segmentation of cardiac structures is one of the fundamental steps to estimate volumetric indices of the heart. This step is still performed semi-automatically in clinical routine, and is thus prone to inter- and intra-observer variability. Recent studies have shown that deep learning has the potential to perform fully automatic segmentation. However, the current best solutions still suffer from a lack of robustness. In this work, we introduce an end-to-end multi-task network designed to improve the overall accuracy of cardiac segmentation while enhancing the estimation of clinical indices and reducing the number of outliers. Results obtained on a large open access dataset show that our method outperforms the current best performing deep learning solution and achieved an overall segmentation accuracy lower than the intra-observer variability for the epicardial border (i.e. on average a mean absolute error of 1.5mm and a Hausdorff distance of 5.1mm) with 11% of outliers. Moreover, we demonstrate that our method can closely reproduce the expert analysis for the end-diastolic and end-systolic left ventricular volumes, with a mean correlation of 0.96 and a mean absolute error of 7.6ml. Concerning the ejection fraction of the left ventricle, results are more contrasted with a mean correlation coefficient of 0.83 and an absolute mean error of 5.0%, producing scores that are slightly below the intra-observer margin. Based on this observation, areas for improvement are suggested.

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