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This paper studies congestion-aware route-planning policies for Autonomous Mobility-on-Demand (AMoD) systems, whereby a fleet of autonomous vehicles provides on-demand mobility under mixed traffic conditions. Specifically, we first devise a network flow model to optimize the AMoD routing and rebalancing strategies in a congestion-aware fashion by accounting for the endogenous impact of AMoD flows on travel time. Second, we capture reactive exogenous traffic consisting of private vehicles selfishly adapting to the AMoD flows in a user-centric fashion by leveraging an iterative approach. Finally, we showcase the effectiveness of our framework with two case-studies considering the transportation sub-networks in Eastern Massachusetts and New York City. Our results suggest that for high levels of demand, pure AMoD travel can be detrimental due to the additional traffic stemming from its rebalancing flows, while the combination of AMoD with walking or micromobility options can significantly improve the overall system performance.