论文标题
沿光学纳米纤维的亚微米脂质囊泡的光学传输
Optical transport of sub-micron lipid vesicles along an optical nanofibre
论文作者
论文摘要
在过去的几年中，使用纳米级介电结构中限制的光进行了对生物粒子进行的操纵和分析。小模式量，以及缺乏对笨重的光学元素的需求，相对于常规光学操纵，具有敏感性和可伸缩性的优势。然而，脂质囊泡（脂质体）的操纵仍然很困难，尤其是在亚微米直径方向上。在这里，我们使用纳米纤维模式的evaneScent场演示了亚微米直径脂质体沿光学纳米纤维的光学诱捕和运输。我们发现低于标称衍射极限的纳米纤维直径可带来最佳的结果。我们的结果为脂质体样生物粒子的光学传输和分析及其与纳米光谐振器的耦合铺平了道路。
Enhanced manipulation and analysis of bio-particles using light confined in nano-scale dielectric structures has proceeded apace in the last several years. Small mode volumes, along with the lack of a need for bulky optical elements give advantages in sensitivity and scalability relative to conventional optical manipulation. However, manipulation of lipid vesicles (liposomes) remains difficult, particularly in the sub-micron diameter regime. Here we demonstrate the optical trapping and transport of sub-micron diameter liposomes along an optical nanofiber using the nanofiber mode's evanescent field. We find that nanofiber diameters below a nominal diffraction limit give optimal results. Our results pave the way for integrated optical transport and analysis of liposome-like bio-particles, as well as their coupling to nano-optical resonators.
