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Stirling permutations were introduced by Gessel and Stanley, who used their enumeration by the number of descents to give a combinatorial interpretation of certain polynomials related to Stirling numbers. Quasi-Stirling permutations, which can be viewed as labeled noncrossing matchings, were introduced by Archer et al. as a natural extension of Stirling permutations. Janson's correspondence between Stirling permutations and labeled increasing plane trees extends to a bijection between quasi-Stirling permutations and the same set of trees without the increasing restriction. Archer et al. posed the problem of enumerating quasi-Stirling permutations by the number of descents, and conjectured that there are $(n+1)^{n-1}$ such permutations of size $n$ having the maximum number of descents. In this paper we prove their conjecture, and we give the generating function for quasi-Stirling permutations by the number of descents, expressed as a compositional inverse of the generating function of Eulerian polynomials. We also find the analogue for quasi-Stirling permutations of the main result from Gessel and Stanley's paper. We prove that the distribution of descents on these permutations is asymptotically normal, and that the roots of the corresponding quasi-Stirling polynomials are all real, in analogy to Bóna's results for Stirling permutations. Finally, we generalize our results to a one-parameter family of permutations that extends $k$-Stirling permutations, and we refine them by also keeping track of the number of ascents and the number of plateaus.