论文标题
汗水中维生素C监测的单步修饰电极
Single-step modified electrodes for vitamin C monitoring in sweat
论文作者
论文摘要
我们演示了一种基于单步修改金微电极在汗液中检测抗坏血酸检测的柔性传感器。修饰是藻酸盐膜的电沉积，在电极顶部被捕获的CuO纳米颗粒。电极在薄的聚酰亚胺支撑下制造，膜的柔软性质可以承受远远超出皮肤监测要求的机械应力。我们进一步显示了在超低施加电位（-5 mV）处的中性缓冲液和酸性人造汗液中微摩尔水平的抗坏血酸的有效检测。汗液中可能存在的干扰物种的影响最小化，没有可观察到的交叉反应，因此尽管制造方案中没有酶，但仍保持高度选择性。该传感器被设想为可穿戴设备的有希望的组件。通过汗液对微量营养素的损失进行非侵入性监测。
We demonstrate a flexible sensor for ascorbic acid detection in sweat based on single-step modified gold microelectrodes. The modification consists on the electrodeposition of alginate membrane with trapped CuO nanoparticles on top of the electrodes. The electrodes are fabricated at a thin polyimide support and the soft nature of the membrane can withstand mechanical stress far beyond the requirements for skin monitoring. We further show the efficient detection of ascorbic acid at the micromolar levels in both, a neutral buffer and acidic artificial sweat, at ultra-low applied potential (-5 mV). The effect of possible interfering species present in sweat is minimized, with no observable cross-reaction, thus maintaining a high degree of selectivity despite absence of enzymes in the fabrication scheme. This sensor is envisioned as a promising component of a wearable device for e.g. non-invasive monitoring of micronutrient loss through sweat.
