论文标题
高温磁性纳米颗粒中的非指数磁弛豫
Non-exponential magnetic relaxation in magnetic nanoparticles for hyperthermia
论文作者
论文摘要
基于磁性纳米颗粒的高温是治疗恶性肿瘤的潜在工具。该方法的效率取决于样品的磁性知识;特别是,对频率依赖的复合磁化敏感性的了解对于优化辐射条件并为材料科学发展提供反馈至关重要。我们首次使用非谐振和谐振射频反射仪研究了水铁氧体悬浮液的频率依赖性磁敏感性。我们使用标准螺线管线圈确定最佳测量条件,该线圈能够提供高达150 MHz的复杂磁化率。结果与从射频谐振器获得的频率匹配的结果与一些离散频率匹配。两种不同方法之间的一致性验证了我们的方法。出人意料的是,即使我们考虑弛豫参数的粒度依赖性分布,动态磁敏感性也无法通过指数磁性弛豫的行为来解释。
Magnetic nanoparticle based hyperthermia emerged as a potential tool for treating malignant tumours. The efficiency of the method relies on the knowledge of magnetic properties of the samples; in particular, knowledge of the frequency dependent complex magnetic susceptibility is vital to optimize the irradiation conditions and to provide feedback for material science developments. We study the frequency-dependent magnetic susceptibility of an aqueous ferrite suspension for the first time using non-resonant and resonant radiofrequency reflectometry. We identify the optimal measurement conditions using a standard solenoid coil, which is capable of providing the complex magnetic susceptibility up to 150 MHz. The result matches those obtained from a radiofrequency resonator for a few discrete frequencies. The agreement between the two different methods validates our approach. Surprisingly, the dynamic magnetic susceptibility cannot be explained by an exponential magnetic relaxation behavior even when we consider a particle size-dependent distribution of the relaxation parameter.