论文标题
不断发展的旋转玻璃模型的尺寸降低:表型反应与环境变化的相关性
Dimensional reduction in evolving spin-glass model: correlation of phenotypic responses to environmental and mutational changes
论文作者
论文摘要
使用统计物理模型研究了高维表型的演变,包括相互作用的旋转,其中基因型,表型和环境分别由自旋构型,相互作用矩阵和外部场表示。我们发现,在所有旋转中,各种环境变化和遗传变异的表型变化都高度相关,这与最近对生物系统的实验性观察一致。表型变化的尺寸降低显示是在复制阶段实现的稳健性向热噪声演变的结果。
The evolution of high-dimensional phenotypes is investigated using a statistical physics model consists of interacting spins, in which genotypes, phenotypes, and environments are represented by spin configurations, interaction matrices, and external fields, respectively. We found that phenotypic changes upon diverse environmental change and genetic variation are highly correlated across all spins, consistent with recent experimental observations of biological systems. The dimension reduction in phenotypic changes is shown to be a result of the evolution of the robustness to thermal noise, achieved at the replica symmetric phase.