ISO/TS TECHNICAL SPECIFICATION 12901-1 First edition 2012-11-15 Nanotechnologies Occupational risk management applied to engineered nanomaterials Part 1: Principles and approaches Nanotechnologies - Management du risque professionnel relatif aux nanomateriauxmanufacturés- Partie 1: Principes et approches Reference number IS0/TS12901-1:2012(E) LSO @ IS0 2012 I without license from IHS Not for Resale IS0/TS 12901-1:2012(E) COPYRIGHTPROTECTEDDOCUMENT ISO2012 All rights reserved. Unless otherwise specified, no part of this publication may be reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying and microfilm, without permission in writing from either IsO at the addressbeloworIso'smemberbodyinthecountryoftherequester. ISO copyright office Case postale 56:CH-1211 Geneva 20 Tel.+41227490111 Fax + 41 22 749 09 47 E-mail [email protected] Web www.iso.org Published in Switzerland @ IS0 2012 - All rights reserved No reproduction networking permited without license from IHS Not for Resale IS0/TS 12901-1:2012(E) Contents Page Foreword ..V Introduction. ...vi 1 Scope. 2 Terms and definitions 3 Symbols and abbreviated terms. 4 Nanomaterial types and characteristics ..4 4.1 General .4 4.2 .5 Fullerenes 4.3 Carbon nanotubes. ..5 4.4 .5 Nanowires 4.5 Quantumdots .5 4.6 Metals and metal oxides, ceramics 4.7 Carbon black ..5 4.8 Dendrimers .6 4.9 Nanoclays. .6 5 Nanomaterial hazard, exposure and risk ..6 5.1 General .. 6 5.2 Potential risk considerations to health from inhalation of NOAAs ..6 5.3 Potential risk considerations to health from dermal exposure or ingestion ..7 5.4 NOAAs as hazardous materials. 5.5 Risk of fire and explosion from NOAAs. ..8 6 General approach to managing risks from NOAAs ..8 7 Identification and competence of person conducting risk assessment. .10 8 Information collection ..11 9 Health risk evaluation ..11 9.1 General .11 9.2 Assessing the hazard. .12 9.3 Assessing exposure. .12 9.4 Assessing and prioritizing health risk. ..13 9.5 Document and review. ..13 10 Control of risk. .13 10.1 Hierarchy of control. .13 10.2 Control of exposure.. ..14 10.3 Selection of controls .15 10.4 Evaluation of the effectiveness of control .16 10.5 Information, instruction and training ..17 11 Measurement methods for evaluating controls .17 11.1 Need for measurement .17 11.2 Selection of instruments .18 11.3 Sampling strategy .20 11.4 Limitations.. .21 12 Health surveillance .22 13 Spillages and accidental releases. .22 14 Disposal procedures. .23 14.1 Planning the storage and disposal of nanomaterials .23 14.2 Storage of nanomaterial waste prior to disposal .23 14.3 Disposal of nanomaterial waste .23 15 Prevention of fire and explosion .24 iii Not for Resale